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Connective Tissue Disease Treatment
Mixed connective tissue disease is more common among women than men. Mixed connective tissue disease occurs worldwide and affects people of all ages, often peaking in incidence during adolescence and the 20s. The cause of mixed connective tissue disease is unknown, but it is an autoimmune disease. The typical symptoms of mixed connective tissue disease are Raynaud syndrome (in which the fingers suddenly become very pale and tingle or become numb or blue in response to cold or emotional upset), joint inflammation (arthritis), swollen hands, muscle weakness, difficulty swallowing, heartburn, and shortness of breath. Raynaud syndrome may precede other symptoms by many years. Regardless of how mixed connective tissue disease starts, it tends to worsen, and symptoms spread to several parts of the body. Almost everyone with mixed connective tissue disease has aching joints. About 75% of people develop the swelling and pain typical of arthritis. Mixed connective tissue disease damages the muscle fibers, so the muscles may feel weak and sore, especially in the shoulders and hips. Tasks such as lifting the arms above the shoulders, climbing stairs, and getting out of a chair can become very difficult.
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