Systemic lupus erythematosus, commonly known as lupus, is an autoimmune illness that affects many organs and systems in the body. Lupus is a chronic condition, but symptoms tend to cycle in alternate periods of "flares" (or "flares-ups") and remissions. There is no known cure, but numerous treatments are available. In a person with lupus, the immune system, which normally protects the body from foreign invaders and infection, malfunctions and instead attacks a person's own healthy body tissues. Lupus can lead to numerous health complications and, in serious cases, can even become life-threatening. The exact cause of lupus is unknown, but most scientists believe that genetics, combined with outside triggers such as infections, medications or other environmental factors – lead to the development of this disease. People with rheumatic diseases and suppressed immune systems, such as lupus patients, may be more vulnerable to the disease known as COVID-19, which is caused by severe acute respiratory syndrome coronavirus 2.

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